Improvement of Chemical Named Entity Recognition through Sentence-based Random Under-sampling and Classifier Combination

Chemical Named Entity Recognition (NER) is the basic step for consequent information extraction tasks such as named entity resolution, drug-drug interaction discovery, extraction of the names of the molecules and their properties. Improvement in the performance of such systems may affects the quality of the subsequent tasks. Chemical text from which data for named entity recognition is extracted is naturally imbalanced since chemical entities are fewer compared to other segments in text. In this paper, the class imbalance problem in the context of chemical named entity recognition has been studied and adopted version of random undersampling for NER data, has been leveraged to generate a pool of classifiers. In order to keep the classes’ distribution balanced within each sentence, the well-known random undersampling method is modified to a sentence based version where the random removal of samples takes place within each sentence instead of considering the dataset as a whole. Furthermore, to take the advantages of combination of a set of diverse predictors, an ensemble of classifiers trained with the set of different training data resulted by sentence-based undersampling, is created. The proposed approach is developed and tested using the ChemDNER corpus released by BioCreative IV. Results show that the proposed method improves the classification performance of the baseline classifiers mainly as a result of an increase in recall. Furthermore, the combination of high performing classifiers trained using undersampled train data surpasses the performance of all single best classifiers and the combination of classifiers using full data.